ea0032p1080 | Thyroid cancer | ECE2013
Faggiano Antongiulio
, Ferolla Piero
, Vitale Giovanni
, Del Prete Michela
, Ramundo Valeria
, Esposito Raffaella
, Marotta Vincenzo
, Marciello Francesca
, Carratu Anna Chiara
, Camera Luigi
, Fonti Rosi
, Colao Annamaria
Introduction: Medullary thyroid cancer (MTC) is a well-differentiated neuroendocrine tumor in which somatostatin receptor (sst) expression is higher for sst1 and sst5 than for sst2. This may explain why the available sst2–selective analogues do not work in these patients and why pasireotide (SOM230), a novel, multi-receptor targeted somatostatin analogue with high-binding affinity for sst1,2,3 and sst5 coul...